Protein Production
Nexomics Biosciences offers a wide variety of protein production services ranging from molecular biology to protein purification, to functional assay development. Custom jobs are welcome.
Bioinformatics & Construct Design
Our experience indicates that truncating or mutating a protein sequence by as little as one amino acid can be the difference between soluble and insoluble protein expression results.
Nexomics Biosciences uses a proprietary approach to identify domain boundaries using a combination of three kinds of data:
- Bioinformatics-based domain boundary and disordered region prediction
- Limited proteolysis with detection by mass spectrometry (MS)
- Amide hydrogen exchange measurements detected by MS (HDX-MS)
Cloning, Expression, & Purification
Primer Design
Maximize PCR success with our automated primer design software, delivering optimal sequences.
Gene Synthesis & Cloning
Harness gene synthesis for challenging sequences and apply domain parsing and mutagenesis techniques effectively.
Large Scale Expression
Benefit from our expertise in large-scale fermentation, supporting diverse expression systems and delivering isotope-enriched samples.
Stable Isotope Labeling
Enhance NMR and mass spectrometry studies with our extensive experience in stable isotope labeling.
Purification
Ensure protein purity with our automated two-step purification process and diverse purification techniques for challenging proteins.
Site-Directed Mutagenesis
Site-directed mutagenesis is used in molecular biology to evaluate functionality as well as structural biology to promote order protein as well as crystallization. Using our protein production platform we can engineer specific mutations into target protein sequences.
Biophysical Characterization
Biophysical Characterization
Utilizing experimental biophysical techniques for quality control and deeper biological system understanding.
Mass Spectroscopy
Employing MALDI-TOF mass spectrometry for quality checks and protein disorder analysis.
Limited Proteolysis
Evaluating protein conformation, secondary structure, and enhancing crystallization propensity.
Static/Dynamic Light Scattering
Confirming protein oligomerization states and aiding in construct optimization for crystallization.
1D/2D NMR
Assessing sample quality, purity, and stability, and screening for ligand interactions.
Biolayer Interferometry
Optical analysis for characterizing biomolecular interactions and affinity determination in assay development.
Functional Assay Development
Functional Assay Development
Partner with us to plan and develop functional assays tailored to your biological system.
Fluorescence Polarization Assays
Rapid, quantitative method for analyzing molecular interactions and enzyme activities.
What We Have Here for You
A descriptive paragraph that tells clients how good you are and proves that you are the best choice that they’ve made.
24x7 Access
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Conference Room
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Printing/FAX
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Gigabit Internet
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Projector
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Week's Supplies
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Flexible Work Space
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Mail Delivery
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Pet Friendly
Augue Velit Cursus Nunc Quis Gravida Magna Mi A Libero.
Frequently Asked Questions
Inventore Veritatis Et Quasi Architecto Beatae Vitae?
Consequ Untur Magni Dolores Eos Voluptatem Sequin?
Inventore Veritatis Et Quasi Architecto Beatae Vitae?
Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit.
Consequ Untur Magni Dolores Eos Voluptatem Sequin?
Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit.