HOME » SERVICES » BIOPHYSICAL CHARACTERIZATION

Mass Spectroscopy
Mass spectroscopy is a powerful technique for experimentally calculating molecular weight. Nexomics Biosciences makes use of MALDI-TOF mass spectroscopy as a quality control check for all protein production projects. The technology can also be used to measure regions of disorder within a protein.

Limited Proteolysis followed by Mass Spectroscopy (LP-MS)
LP-MS is another experimental technique that can often reveal regions of disorder within a native protein structure. While not as sensitive as DX-MS it often provides a faster/cheaper method to evaluate disorder.

Analytical Gel Filtration followed by Static/Dynamic Light Scattering
This powerful technique is used to experimentally calculate protein oligmeric state. Often for structural biology studies it is necessary to be sure of the primary oligmeric state of the native protein. Nexomics Biosciences has extensive expertise in measuring target protein oligmeric state by combining gel filtration with light scattering techniques.


DNA Sequencing
Natural sequence mutation and molecular cloning errors due to lack of primer specificity are common issues that must be dealt with in molecular biology. Nexomics is able to offer DNA sequencing as a quality control check against human and natural error.

Protein Sequencing
Often it is necessary to confirm sequence at the protein level. Through its Mass Spectroscopy capabilities Nexomics Biosciences offers protein sequencing as a service.